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Working volume from 10 - 35 000 Liters.
Novel magnetic coupling agitator – top or bottom mounted.
Aeration through ring sparger with aeration rate up to 2 vvm.
Controls flows of steam, water and gases to ensure fermentation, CIP and automatic sterilization processes.
Vessel produced from certified surgical steel 316L
Manufactured adhering to the highest standards of quality and innovation
Pilot Scale Bioreactors
The Pilot scale series, in standard configuration, SIP fermenters/bioreactors are available in a wide range of working volumes from 10 – 35000 L liters, with multiple variations and customization options. Choose one of the Standard versions of Pilot Scale fermenters/bioreactors or customize Your own using the configurator. All pilot bioreactors are fully custom made to meet your specific needs.
Our configurator makes it easy to prepare a request and add additional features:
The models with working volume from 10 to 350 L are the perfect choice for scaling up bioprocesses from Lab scale and for initiating a small scale production before industrial scale-up. For larger volume fermenters/bioreactors use our configurator to specify reactor design or send Your request via email with Technical Specification and requirements.
All stainless-steel bioreactors with working volume from 10 – 35000 L are autonomous and consist of three main parts:
Technological skid and fermenter/bioreactor vessel can be interconnected with Corrugated PTFE hoses reinforced with single stainless steel (AISI 304) braid or could be integrated within a single frame.
Summary
Fermenter/Bioreactor vessel has an insulated jacket. (Insulation – mineral wool) thickness varies from 50 to 100 mm. Insulation is plated with Stainless steel (AISI 304). Vessel can be equipped with flat or torispherically flanged, moveable lid (till 800 L). Larger vessels are equipped with a manhole of corresponding size to ensure serviceability and maintenance.
Novel magnetic coupling agitator – top or bottom mounted. For microbial cultures 2-3 Rushton turbines are used to mix the media. Optionally pitched blade or marine impellers are available for shear sensitive conditions.
Aeration through ring sparger with aeration rate up to 2 vvm.
Optionally air supply overlay, mass flow controllers (MFC), addition up to four different gases: (Oxygen, Nitrogen, Carbon Dioxide).
Aeration system includes:
Stainless steel control cabinet (Rittal, Germany) with built-in Siemens PLC and Weintek touch panel. Profinet connection to LAN or WAN
Automatic process control is ensured by the following sensors:
*Stainless steel control cabinet (Rittal, Germany) with built-in Siemens PLC and Weintek touch panel. Profinet connection to LAN or WAN
In customized versions several optional sensors are available:
Technical Specification describes Pilot Scale fermenters/bioreactors with working volume from 10 – 350 liters in Standard configurations. For customization or different configuration purposes use our configurator to prepare Your request.
Technological skid – system of pipes, valves and sensors which ensure supply of technological medias to the vessel – air, steam, clean steam, water as well as cooling water and condensate return from the system. Sensors and valves ensure fully automated process control.
Several processes can be performed in automatic mode:
